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Unser einzigartiges Produktionssystem liefert Proben amyloider Proteine und Peptide in höchster Qualität

Fibrillen aus rekombinant hergestelltem ɑ-Synuclein, dem Schlüsselprotein der Parkinson-Krankheit


Die Forschung zu zahlreichen schwerwiegenden Erkrankungen, wie Alzheimer, Parkinson oder Diabetes Typ 2, ist angewiesen auf hochreine Proben der beteiligten amyloiden Proteine und Peptide.

Aufgrund ihrer schädlichen Wirkung auf den produzierenden Organismus lassen sich diese oft nur sehr schwer rekombinant herstellen.

Das innovative und auf der Basis langjähriger strukturbiologischer Erfahrung entwickelte System der Isoloid GmbH, einer Ausgründung der Heinrich-Heine-Universität Düsseldorf und des Forschungszentrums Jülich, liefert hochreine Proben für Ihr Labor.

Die hohe Qualität schafft eine verlässliche Basis für Forschungsprojekte. Auch die Markierung mit stabilen Isotopen zur Analyse mit Hilfe der NMR-Spektroskopie ist sehr leicht möglich.

Wir freuen uns auf ihre Anfrage!

Isoloid GmbH
CEO, Stefan Klinker

Erkrather Str. 401
40231 Düsseldorf

Produktdetails

Description

Product name: Beta-amyloid protein 40
Synonyms: Abeta1-40, Abeta40
Protein length: Full length protein
Catalogue number: ab40_15N
Nature: Recombinant
Source: E. coli
Amino acid sequence: P05067
Isotopic labeling: 15N
Species: Human
Amino acids: 40
Tags: None
Additional sequence information: aa 672 – 711 encodes for the Beta-amyloid protein 42, cleaved from the Amyloid beta A4 protein.
Applications: Various
Purity: > 95 % by RP HPLC
Form: Lyophilised
Concentration: Reconstitution dependent

Preparation and Storage

Stability and storage: Shipped at RT. Store at -80°C for long term. Avoid freeze / thaw cycle.
Preservative: None
Constituents: TFA
Reconstitution: Before reconstitution please incubate ON with HFIP (> 200 µl/mg) and lyophilise again. Afterwards reconstitute in desired buffer. Mind concentration dependent aggregation behaviour.
Additional info: http://www.uniprot.org/uniprot/P05067

Description

Product name: Beta-amyloid protein 40
Synonyms: Abeta1-40, Abeta40
Protein length: Full length protein
Catalogue number: ab40_15N13C
Nature: Recombinant
Source: E. coli
Amino acid sequence: P05067
Isotopic labeling: 15N, 13C
Species: Human
Amino acids: 40
Tags: None
Additional sequence information: aa 672 – 711 encodes for the Beta-amyloid protein 42, cleaved from the Amyloid beta A4 protein.
Applications: Various
Purity: > 95 % by RP HPLC
Form: Lyophilised
Concentration: Reconstitution dependent

Preparation and Storage

Stability and storage: Shipped at RT. Store at -80°C for long term. Avoid freeze / thaw cycle.
Preservative: None
Constituents: TFA
Reconstitution: Before reconstitution please incubate ON with HFIP (> 200 µl/mg) and lyophilise again. Afterwards reconstitute in desired buffer. Mind concentration dependent aggregation behaviour.
Additional info: http://www.uniprot.org/uniprot/P05067

Description

Product name: Beta-amyloid protein 42
Synonyms: Abeta1-42, Abeta42
Protein length: Full length protein
Catalogue number: ab42_15N13C
Nature: Recombinant
Source: E. coli
Amino acid sequence: P05067
Isotopic labeling: 15N, 13C
Species: Human
Amino acids: 42
Tags: None
Additional sequence information: aa 672 – 713 encodes for the Beta-amyloid protein 42, cleaved from the Amyloid beta A4 protein.
Applications: Various
Purity: > 95 % by RP HPLC
Form: Lyophilised
Concentration: Reconstitution dependent

Preparation and Storage

Stability and storage: Shipped at RT. Store at -80°C for long term. Avoid freeze / thaw cycle.
Preservative: None
Constituents: TFA
Reconstitution: Before reconstitution please incubate ON with HFIP (> 200 µl/mg) and lyophilise again. Afterwards reconstitute in desired buffer. Mind concentration dependent aggregation behaviour.
Additional info: http://www.uniprot.org/uniprot/P05067

Description

Product name: Beta-amyloid protein 42
Synonyms: Abeta1-42, Abeta42
Protein length: Full length protein
Catalogue number: ab42_15N
Nature: Recombinant
Source: E. coli
Amino acid sequence: P05067
Isotopic labeling: 15N
Species: Human
Amino acids: 42
Tags: None
Additional sequence information: aa 672 – 713 encodes for the Beta-amyloid protein 42, cleaved from the Amyloid beta A4 protein.
Applications: Various
Purity: > 95 % by RP HPLC
Form: Lyophilised
Concentration: Reconstitution dependent

Preparation and Storage

Stability and storage: Shipped at RT. Store at -80°C for long term. Avoid freeze / thaw cycle.
Preservative: None
Constituents: TFA
Reconstitution: Before reconstitution please incubate ON with HFIP (> 200 µl/mg) and lyophilise again. Afterwards reconstitute in desired buffer. Mind concentration dependent aggregation behaviour.
Additional info: http://www.uniprot.org/uniprot/P05067

Description

Product name: Islet Amyloid Polypeptide
Synonyms: Amylin, IAPP
Protein length: 37 amino acid polypeptide
Catalogue number: IAPP_15N13C
Nature: Recombinant
Source: E. coli
Amino acid sequence: P10997
Isotopic labeling: 15N 13C
Species: Human
Amino acids: 37
Tags: None
Additional sequence information: aa 34-70 encode for processed islet amyloid polypeptide.
Applications: Various
Purity: > 95 % by RP HPLC
Form: Lyophilised
Concentration: Reconstitution dependent

Preparation and Storage

Stability and storage: Shipped at RT. Store at -80°C for long term. Avoid freeze / thaw cycle.
Preservative: None
Constituents: TFA
Reconstitution: Before reconstitution please incubate ON with HFIP (> 200 µl/mg) and lyophilise again. Afterwards reconstitute in desired buffer. Mind concentration dependent aggregation behaviour.

Preisliste 2015

Produkt Preis in € / 1 mg
Amyloid Beta (1-40) HFIP 15N 475
Amyloid Beta (1-40) HFIP 15N 13C 1939
Amyloid Beta (1-42) HFIP 15N 559
Amyloid Beta (1-42) HFIP 15N 13C 2129
Amyloid Beta (3-40) Pyroglutamat HFIP 15N 959
Amyloid Beta (3-40) Pyroglutamat HFIP 15N 13C 3879
Amyloid Beta (3-42) Pyroglutamat HFIP 15N 1115
Amyloid Beta (3-42) Pyroglutamat HFIP 15N 13C 4245
Produkt Preis in € / 1 mg
α-synuclein 15N 600
α-synuclein 15N 13C 3280
Produkt Preis in € / 1 mg
humanes PrPc „full length“ 23-231 native, zelluläre Form 15N 2995
humanes PrPc „full length“ 23-231 native, zelluläre Form 15N 13C 9685
humanes PrPc 90-231 native, zelluläre Form 15N 2995
humanes PrPc 90-231 native, zelluläre Form 15N 13C 9685
humanes PrPc 23-144 native, zelluläre Form 15N 2995
humanes PrPc 23-144 native, zelluläre Form 15N 13C 9685
Produkt Preis in € / 1 mg
Amylin 15N 1195
Amylin 15N 13C 4195

Details

Preisangaben ohne Gewähr, Änderungen vorbehalten. Lieferzeiten auf Anfrage.

Abweichende Abnahmemengen, Isotopenmuster, Sequenzvarianten und Isoformen auf Anfrage.

Alle Peptide und Proteine sind auf ihre homogene und ggf. native Konformation (im Falle von PrP) durch NMR-Spektroskopie überprüft.


Preisliste herunterladen